PATHOLOGICAL COMPLETE RESPONSE WITH NEOADJUVANT TRASTUZUMAB COMBINED WITH CHEMOTHERAPY IN HER2 POSITIVE BREAST CANCER: A SINGLE INSTITUTION RETROSPECTIVE ANALYSIS FROM VIETNAM

Huyen Thi Phung,1 Hoa Thi Nguyen,1 Tung Van Nguyen,1 Tai Van Nguyen,2 Lan Anh Thi Dinh,3 Chu Van Nguyen4 1Department of Medical Oncology 6, National Cancer Hospital of Vietnam, Hanoi, Vietnam; 2Department of Medical Oncology 1, National Cancer Hospital of Vietnam, Hanoi, Vietnam; 3Department of Optimal Therapy, Quan Su Campus, National Cancer Hospi

Abstract As a strategy to improve the therapeutic success of chimeric antigen receptor T cells (CART) directed against solid tumors, we here test the combinatorial use of CART and IMSA101, a newly developed stimulator of interferon genes (STING) agonist.In two syngeneic tumor models, improved overall survival is observed when mice are treated with

Abstract Eicosanoids are major players in the pathogenesis of several common diseases, with either overproduction or imbalance (e.g.between thromboxanes and Suspension Control Arm prostacyclins) often leading to worsening of disease symptoms.Both the total rate of eicosanoid production and the balance between eicosanoids with opposite effects are s

Background: Accumulating research demonstrates that the timing of exercise plays an important role in influencing episodic memory.However, we have a limited understanding as to the factors that moderate this temporal effect.Thus, the purpose of this systematic review with meta-analysis was to evaluate the effects of study characteristics (e.g., exe